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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
31.21
Human Site:
S412
Identified Species:
62.42
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S412
L
D
R
I
G
S
L
S
Q
R
F
K
D
T
R
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S414
L
D
R
I
G
S
L
S
Q
R
F
K
D
T
R
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
S384
M
D
L
V
S
S
L
S
R
T
Y
K
E
S
R
Dog
Lupus familis
XP_546737
807
92419
S440
L
D
R
I
S
S
L
S
Q
R
F
K
D
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S398
L
D
R
I
G
S
L
S
Q
R
F
K
E
A
R
Rat
Rattus norvegicus
P0C1T0
774
89178
S407
L
D
R
I
G
S
L
S
Q
R
F
K
E
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
S382
I
D
R
V
S
S
L
S
R
R
F
K
D
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
S388
M
D
R
V
S
S
M
S
R
R
F
K
D
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
I485
M
S
L
M
S
H
M
I
D
E
Y
Q
R
E
R
Honey Bee
Apis mellifera
XP_392502
776
89056
I412
M
S
I
M
P
H
M
I
D
E
Y
Q
Q
K
R
Nematode Worm
Caenorhab. elegans
O16796
848
97043
D482
Q
S
N
V
R
Y
L
D
E
R
F
E
D
I
K
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
S400
K
L
R
V
M
N
L
S
K
R
F
Q
A
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
40
86.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
60
N.A.
6.6
6.6
26.6
33.3
P-Site Similarity:
100
100
80
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
86.6
N.A.
40
40
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
0
9
17
0
0
0
50
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
17
0
9
25
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
42
0
0
0
17
0
0
0
0
0
9
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
0
0
67
0
9
9
% K
% Leu:
42
9
17
0
0
0
75
0
0
0
0
0
0
0
0
% L
% Met:
34
0
0
17
9
0
25
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
0
42
0
0
25
9
0
0
% Q
% Arg:
0
0
67
0
9
0
0
0
25
75
0
0
9
0
84
% R
% Ser:
0
25
0
0
42
67
0
75
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
17
0
% T
% Val:
0
0
0
42
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _